Researchers image atomic structure of important immune regulator

Understanding structure of human TIM-3 provides new insights for cancer and autoimmune drug development Credit: Richard Blumberg, Brigham and Women’s Hospital A new study by investigators from Brigham and Women’s Hospital provides a biophysical and structural assessment of a critical immune regulating protein called human T-cell immunoglobulin and mucin domain containing protein-3 (hTIM-3). Understanding the […]

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The surprising upward link between college alcohol consumption and physical activity

Study to examine why those who exercise more drink most Credit: University of Houston Upending conventional wisdom that physical activity can be a healthy deterrent to alcohol consumption, University of Houston Moores professor of psychology Clayton Neighbors is examining the relationship between the two in college students. In prior work, Neighbors concluded that as activity […]

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Two compounds in coffee may team up to fight Parkinson’s

Caffeine plus another compound in coffee beans’ waxy coating may protect against brain degeneration, Rutgers study finds Credit: Steve Hockstein/Harvard Studio Rutgers scientists have found a compound in coffee that may team up with caffeine to fight Parkinson’s disease and Lewy body dementia – two progressive and currently incurable diseases associated with brain degeneration. The […]

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When scientists push people to their tipping point

We’re bad at knowing when we will fall — or when we’re upright Credit: Ohio State University COLUMBUS, Ohio – You probably overestimate just how far someone can push you before you reach your tipping point, new research suggests. No, we’re not talking about your emotional tipping point. A new study examined how far people […]

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How to survive on ‘Game of Thrones’: Switch allegiances

Credit: Dr. Reidar Lystad, 2018 Characters in the Game of Thrones TV series are more likely to die if they do not switch allegiance, and are male, according to an article published in the open access journal Injury Epidemiology. Researchers at Macquarie University, Australia, evaluated the deaths of all important Game of Thrones characters across […]

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Middle aged men in lyrca on the rise but ‘Mamils’ confined to weekends, affluent suburb

Credit: MJA University of Sydney authors who led the research said the Mamil study was prompted by media attention given to depicting and satirising this group and the importance of physical activity for preventing lifestyle diseases like cardiovascular disease. “The origins of the Mamil species are unclear, but the first descriptions, from around 2010, were […]

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Potential seen for tailoring treatment for acute myeloid leukemia

Rapid drug response screening for leukemia stem cells offers clues to relapse and to improving patient-specific therapies Credit: Alice C, Gray Advances in rapid screening of leukemia cells for drug susceptibility and resistance are bringing scientists closer to patient-tailored treatment for acute myeloid leukemia (AML). Research on the drug responses of leukemia stem cells may […]

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New generation of therapeutics based on understanding of aging biology show promise for Alzheimer’s disease

Credit: ADDF logo A review published in Neurology┬« explores novel approaches beyond the common amyloid that could slow or prevent Alzheimer’s Experts say combination therapy for Alzheimer’s disease likely needed for better treatment outcomes, similar to heart disease and cancer NEW YORK, NY, December 7, 2018: A scientific strategy that explores therapeutic targets based on […]

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UC San Diego researcher gets $4 million NCI award to study cancer drug resistance, spread

Credit: UC San Diego Health The National Cancer Institute (NCI) has awarded David Cheresh, PhD, Distinguished Professor and vice chair of Pathology at University of California San Diego School of Medicine, with a $4.2 million Outstanding Investigator Award to continue his research into cancer’s ability to overcome stress, gain drug resistance and metastasize. The Outstanding […]

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Carnegie Mellon researchers probe hydrogen bonds using new technique

Credit: Carnegie Mellon University Researchers at Carnegie Mellon University have used nuclear resonance vibrational spectroscopy to probe the hydrogen bonds that modulate the chemical reactivity of enzymes, catalysts and biomimetic complexes. The technique could lead to the development of better catalysts for use in a wide range of fields. The findings were published as a […]

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